7shi

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<StructureSection load='7shi' size='340' side='right'caption='[[7shi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='7shi' size='340' side='right'caption='[[7shi]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7shi]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SHI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7shi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_nodosus Streptomyces nodosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7SHI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7SHI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UH:(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,22E,33S,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,22-diene-36-carboxylic+acid'>4UH</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.0000277&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UH:(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,22E,33S,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,22-diene-36-carboxylic+acid'>4UH</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7shi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7shi OCA], [https://pdbe.org/7shi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7shi RCSB], [https://www.ebi.ac.uk/pdbsum/7shi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7shi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7shi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7shi OCA], [https://pdbe.org/7shi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7shi RCSB], [https://www.ebi.ac.uk/pdbsum/7shi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7shi ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q93NX6_9ACTN Q93NX6_9ACTN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Amaya, J A]]
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[[Category: Streptomyces nodosus]]
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[[Category: Poulos, T L]]
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[[Category: Amaya JA]]
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[[Category: Amphotericin b]]
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[[Category: Poulos TL]]
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[[Category: Cytochrome]]
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[[Category: Hydroxylase]]
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[[Category: Oxidoreductase]]
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[[Category: P450]]
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Revision as of 16:51, 18 October 2023

Crystal Structure of Cytochrome P450 AmphL from Streptomyces nodosus and the Structural Basis for Substrate Selectivity in Macrolide Metabolizing P450s

PDB ID 7shi

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