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5lh4

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<StructureSection load='5lh4' size='340' side='right'caption='[[5lh4]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
<StructureSection load='5lh4' size='340' side='right'caption='[[5lh4]], [[Resolution|resolution]] 1.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lh4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LH4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LH4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lh4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LH4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6W4:(2~{S},4~{S})-1-[4-(aminomethyl)phenyl]carbonyl-4-(4-cyclopropyl-1,2,3-triazol-1-yl)-~{N}-(2,2-diphenylethyl)pyrrolidine-2-carboxamide'>6W4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.37&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6W4:(2~{S},4~{S})-1-[4-(aminomethyl)phenyl]carbonyl-4-(4-cyclopropyl-1,2,3-triazol-1-yl)-~{N}-(2,2-diphenylethyl)pyrrolidine-2-carboxamide'>6W4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lh4 OCA], [http://pdbe.org/5lh4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lh4 RCSB], [http://www.ebi.ac.uk/pdbsum/5lh4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lh4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lh4 OCA], [https://pdbe.org/5lh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lh4 RCSB], [https://www.ebi.ac.uk/pdbsum/5lh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lh4 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5lh4" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5lh4" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Trypsin 3D structures|Trypsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Brandl T]]
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[[Category: Arcy, A D]]
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[[Category: D'Arcy A]]
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[[Category: Brandl, T]]
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[[Category: Schiering N]]
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[[Category: Schiering, N]]
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[[Category: Simic O]]
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[[Category: Simic, O]]
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[[Category: Skaanderup P]]
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[[Category: Skaanderup, P]]
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[[Category: Woelcke J]]
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[[Category: Woelcke, J]]
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[[Category: Complex]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Pancreatitis]]
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[[Category: S1 protease]]
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Revision as of 18:25, 18 October 2023

Trypsin inhibitors for the treatment of pancreatitis - cpd 1

PDB ID 5lh4

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