5lj9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:29, 18 October 2023) (edit) (undo)
 
Line 1: Line 1:
==Structure of the E. coli MacB ABC domain (C2221)==
==Structure of the E. coli MacB ABC domain (C2221)==
-
<StructureSection load='5lj9' size='340' side='right' caption='[[5lj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='5lj9' size='340' side='right'caption='[[5lj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5lj9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LJ9 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5lj9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LJ9 FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">macB, ybjZ, b0879, JW0863 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lj9 OCA], [http://pdbe.org/5lj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lj9 RCSB], [http://www.ebi.ac.uk/pdbsum/5lj9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lj9 ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lj9 OCA], [https://pdbe.org/5lj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lj9 RCSB], [https://www.ebi.ac.uk/pdbsum/5lj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lj9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/MACB_ECOLI MACB_ECOLI]] Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. When overexpressed, the system confers resistance against macrolides composed of 14- and 15-membered lactones but no or weak resistance against 16-membered ones. In addition, the system could also transport R-LPS or a similar glycolipid.<ref>PMID:11544226</ref> <ref>PMID:17214741</ref> <ref>PMID:18955484</ref> <ref>PMID:23974027</ref>
+
[https://www.uniprot.org/uniprot/MACB_ECOLI MACB_ECOLI] Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. When overexpressed, the system confers resistance against macrolides composed of 14- and 15-membered lactones but no or weak resistance against 16-membered ones. In addition, the system could also transport R-LPS or a similar glycolipid.<ref>PMID:11544226</ref> <ref>PMID:17214741</ref> <ref>PMID:18955484</ref> <ref>PMID:23974027</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ecoli]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Crow, A]]
+
[[Category: Large Structures]]
-
[[Category: Abc transporter]]
+
[[Category: Crow A]]
-
[[Category: Membrane protein]]
+
-
[[Category: Transport protein]]
+

Current revision

Structure of the E. coli MacB ABC domain (C2221)

PDB ID 5lj9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools