5ltg

<StructureSection load='5ltg' size='340' side='right' caption='[[5ltg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>

<table><tr><td colspan='2'>[[5ltg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_7073 Cbs 7073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LTG FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATG18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=870730 CBS 7073])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ltg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ltg OCA], [http://pdbe.org/5ltg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ltg RCSB], [http://www.ebi.ac.uk/pdbsum/5ltg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ltg ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/ATG18_PICAN ATG18_PICAN]] The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

[[Category: Cbs 7073]]

[[Category: Kuhnel, K]]

[[Category: Scacioc, A]]

[[Category: Lipid binding protein]]

[[Category: Membrane binding protein]]