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5lty

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Current revision (18:49, 18 October 2023) (edit) (undo)
 
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==Homeobox transcription factor CDX2 bound to methylated DNA==
==Homeobox transcription factor CDX2 bound to methylated DNA==
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<StructureSection load='5lty' size='340' side='right' caption='[[5lty]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
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<StructureSection load='5lty' size='340' side='right'caption='[[5lty]], [[Resolution|resolution]] 2.66&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5lty]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LTY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5lty]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5LTY FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.66&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDX2, CDX3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lty OCA], [http://pdbe.org/5lty PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lty RCSB], [http://www.ebi.ac.uk/pdbsum/5lty PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lty ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5lty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lty OCA], [https://pdbe.org/5lty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5lty RCSB], [https://www.ebi.ac.uk/pdbsum/5lty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5lty ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CDX2_HUMAN CDX2_HUMAN]] Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
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[https://www.uniprot.org/uniprot/CDX2_HUMAN CDX2_HUMAN] Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Morgunova, E]]
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[[Category: Large Structures]]
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[[Category: Popov, A]]
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[[Category: Morgunova E]]
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[[Category: Taipale, J]]
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[[Category: Popov A]]
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[[Category: Methylated dna]]
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[[Category: Taipale J]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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Current revision

Homeobox transcription factor CDX2 bound to methylated DNA

PDB ID 5lty

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