8k4n

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m (Protected "8k4n" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8k4n is ON HOLD
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==Structure of GPR34-Gi complex==
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<StructureSection load='8k4n' size='340' side='right'caption='[[8k4n]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
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Authors: Wong, T.S., Zeng, Z.C., Xiong, T.T., Gan, S.Y., He, G.D., Du, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8k4n]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K4N FirstGlance]. <br>
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Description: Structure of GPR34-Gi complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VF0:(2R)-2-azanyl-3-[oxidanyl-[(2R)-2-oxidanyl-3-tetradec-9-enoyloxy-propoxy]phosphoryl]oxy-propanoic+acid'>VF0</scene></td></tr>
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[[Category: Xiong, T.T]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k4n OCA], [https://pdbe.org/8k4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k4n RCSB], [https://www.ebi.ac.uk/pdbsum/8k4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k4n ProSAT]</span></td></tr>
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[[Category: Wong, T.S]]
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</table>
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[[Category: He, G.D]]
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== Function ==
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[[Category: Zeng, Z.C]]
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[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
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[[Category: Du, Y]]
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== References ==
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[[Category: Gan, S.Y]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Synthetic construct]]
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[[Category: Du Y]]
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[[Category: Gan SY]]
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[[Category: He GD]]
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[[Category: Wong TS]]
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[[Category: Xiong TT]]
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[[Category: Zeng ZC]]

Revision as of 07:06, 25 October 2023

Structure of GPR34-Gi complex

PDB ID 8k4n

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