1npa

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[[Image:1npa.jpg|left|200px]]
[[Image:1npa.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 1npa |SIZE=350|CAPTION= <scene name='initialview01'>1npa</scene>, resolution 2.&Aring;
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The line below this paragraph, containing "STRUCTURE_1npa", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=3NH:(3S)-TETRAHYDROFURAN-3-YL+(1R,2S)-3-[4-((1R)-2-{[(S)-AMINO(HYDROXY)METHYL]OXY}-2,3-DIHYDRO-1H-INDEN-1-YL)-2-BENZYL-3-OXOPYRROLIDIN-2-YL]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>3NH</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
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-->
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|DOMAIN=
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{{STRUCTURE_1npa| PDB=1npa | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1npa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1npa OCA], [http://www.ebi.ac.uk/pdbsum/1npa PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1npa RCSB]</span>
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}}
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'''crystal structure of HIV-1 protease-hup'''
'''crystal structure of HIV-1 protease-hup'''
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[[Category: Sprengeler, P A.]]
[[Category: Sprengeler, P A.]]
[[Category: Yao, W.]]
[[Category: Yao, W.]]
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[[Category: aspartyl protease]]
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[[Category: Aspartyl protease]]
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[[Category: hiv]]
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[[Category: Hiv]]
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[[Category: protease]]
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[[Category: Protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:48:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:33:34 2008''
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Revision as of 23:48, 2 May 2008

Template:STRUCTURE 1npa

crystal structure of HIV-1 protease-hup


About this Structure

1NPA is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

An orally bioavailable pyrrolinone inhibitor of HIV-1 protease: computational analysis and X-ray crystal structure of the enzyme complex., Smith AB 3rd, Hirschmann R, Pasternak A, Yao W, Sprengeler PA, Holloway MK, Kuo LC, Chen Z, Darke PL, Schleif WA, J Med Chem. 1997 Aug 1;40(16):2440-4. PMID:9258349 Page seeded by OCA on Sat May 3 02:48:40 2008

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OCA

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