1wy2

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Current revision (08:01, 25 October 2023) (edit) (undo)
 
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<StructureSection load='1wy2' size='340' side='right'caption='[[1wy2]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='1wy2' size='340' side='right'caption='[[1wy2]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1wy2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WY2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1wy2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WY2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Xaa-Pro_dipeptidase Xaa-Pro dipeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.13.9 3.4.13.9] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy2 OCA], [https://pdbe.org/1wy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wy2 RCSB], [https://www.ebi.ac.uk/pdbsum/1wy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wy2 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wy2 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wy2 OCA], [https://pdbe.org/1wy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wy2 RCSB], [https://www.ebi.ac.uk/pdbsum/1wy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wy2 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wy2 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PEPQ_PYRHO PEPQ_PYRHO]] Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position (By similarity).
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[https://www.uniprot.org/uniprot/PEPQ_PYRHO PEPQ_PYRHO] Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Xaa-Pro dipeptidase]]
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[[Category: Kunishima N]]
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[[Category: Kunishima, N]]
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[[Category: Mizutani H]]
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[[Category: Mizutani, H]]
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[[Category: Structural genomic]]
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[[Category: Hydrolase]]
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[[Category: Prolidase]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3

PDB ID 1wy2

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