1z1x
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1X FirstGlance]. <br> | <table><tr><td colspan='2'>[[1z1x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Echis_carinatus Echis carinatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z1X FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1x OCA], [https://pdbe.org/1z1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1x RCSB], [https://www.ebi.ac.uk/pdbsum/1z1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1x ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z1x OCA], [https://pdbe.org/1z1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z1x RCSB], [https://www.ebi.ac.uk/pdbsum/1z1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z1x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DID_ECHCA DID_ECHCA] Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 26: | Line 26: | ||
[[Category: Echis carinatus]] | [[Category: Echis carinatus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bilgrami | + | [[Category: Bilgrami S]] |
| - | [[Category: Ethayathulla | + | [[Category: Ethayathulla AS]] |
| - | [[Category: Hassan | + | [[Category: Hassan MI]] |
| - | [[Category: Singh | + | [[Category: Singh B]] |
| - | [[Category: Singh | + | [[Category: Singh TP]] |
| - | [[Category: Yadav | + | [[Category: Yadav S]] |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 08:13, 25 October 2023
Crystal Structure of a novel disintegrin from Saw-scaled viper at 3.2 A resolution
| |||||||||||
