2d0n
From Proteopedia
(Difference between revisions)
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<StructureSection load='2d0n' size='340' side='right'caption='[[2d0n]], [[Resolution|resolution]] 1.57Å' scene=''> | <StructureSection load='2d0n' size='340' side='right'caption='[[2d0n]], [[Resolution|resolution]] 1.57Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2d0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2d0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D0N FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d0n OCA], [https://pdbe.org/2d0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d0n RCSB], [https://www.ebi.ac.uk/pdbsum/2d0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d0n ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d0n OCA], [https://pdbe.org/2d0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d0n RCSB], [https://www.ebi.ac.uk/pdbsum/2d0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d0n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/GRAP2_MOUSE GRAP2_MOUSE] Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Mus musculus]] |
- | [[Category: Dimasi | + | [[Category: Dimasi N]] |
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Current revision
Crystal structure of the C-terminal SH3 domain of the adaptor protein GADS in complex with SLP-76 motif peptide reveals a unique SH3-SH3 interaction
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