2d7s
From Proteopedia
(Difference between revisions)
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<StructureSection load='2d7s' size='340' side='right'caption='[[2d7s]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2d7s' size='340' side='right'caption='[[2d7s]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2d7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and- | + | <table><tr><td colspan='2'>[[2d7s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot_and_mouth_disease_virus_C Foot and mouth disease virus C] and [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus_C-S8c1 Foot-and-mouth disease virus C-S8c1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D7S FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7s OCA], [https://pdbe.org/2d7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7s RCSB], [https://www.ebi.ac.uk/pdbsum/2d7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7s ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7s OCA], [https://pdbe.org/2d7s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7s RCSB], [https://www.ebi.ac.uk/pdbsum/2d7s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/Q9QCE4_9PICO Q9QCE4_9PICO] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: Foot-and-mouth disease virus | + | [[Category: Foot and mouth disease virus C]] |
+ | [[Category: Foot-and-mouth disease virus C-S8c1]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | + | [[Category: Arias A]] | |
- | [[Category: Arias | + | [[Category: Domingo E]] |
- | [[Category: Domingo | + | [[Category: Escarmis C]] |
- | [[Category: Escarmis | + | [[Category: Ferrer-Orta C]] |
- | [[Category: Ferrer-Orta | + | [[Category: Perez-Luque R]] |
- | [[Category: Perez-Luque | + | [[Category: Verdaguer N]] |
- | [[Category: Verdaguer | + | |
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Current revision
Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein
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