2dc6
From Proteopedia
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<StructureSection load='2dc6' size='340' side='right'caption='[[2dc6]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2dc6' size='340' side='right'caption='[[2dc6]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dc6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2dc6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DC6 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=73V:BENZYL+N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE'>73V</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=73V:BENZYL+N-({(2S,3S)-3-[(PROPYLAMINO)CARBONYL]OXIRAN-2-YL}CARBONYL)-L-ISOLEUCYL-L-PROLINATE'>73V</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dc6 OCA], [https://pdbe.org/2dc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dc6 RCSB], [https://www.ebi.ac.uk/pdbsum/2dc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dc6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dc6 OCA], [https://pdbe.org/2dc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dc6 RCSB], [https://www.ebi.ac.uk/pdbsum/2dc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dc6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATB_BOVIN CATB_BOVIN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bos taurus]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Watanabe | + | [[Category: Watanabe D]] |
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Revision as of 08:25, 25 October 2023
X-ray crystal structure analysis of bovine spleen cathepsin B-CA073 complex
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