This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2dvx
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='2dvx' size='340' side='right'caption='[[2dvx]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2dvx' size='340' side='right'caption='[[2dvx]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_sp. Rhizobium sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DVX FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2dvx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhizobium_sp._MTP-10005 Rhizobium sp. MTP-10005]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DVX FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=23A:2,3-DIHYDROXYBENZALDEHYDE'>23A</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dvx OCA], [https://pdbe.org/2dvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dvx RCSB], [https://www.ebi.ac.uk/pdbsum/2dvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dvx ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dvx OCA], [https://pdbe.org/2dvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dvx RCSB], [https://www.ebi.ac.uk/pdbsum/2dvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dvx ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GRDC_RHIS5 GRDC_RHIS5] Involved in the gamma-resorcylate (2,6-dihydroxybenzoate) catabolism (PubMed:15466039). Catalyzes the reversible decarboxylation of gamma-resorcylate to resorcinol (PubMed:15466039). The reaction is reversible, but equilibrium greatly favors the decarboxylation reaction (PubMed:15466039). Also catalyzes the decarboxylation of 2,3-dihydroxybenzoate to catechol, but does not act on 2,4-dihydroxybenzoate, 2,5-dihydroxybenzoate, 3,4-dihydroxybenzoate, 3,5-dihydroxybenzoate, 2-hydroxybenzoate, or 3-hydroxybenzoate. Only resorcinol is carboxylated by the reverse reaction (PubMed:15466039).<ref>PMID:15466039</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 18: | Line 20: | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dvx ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dvx ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Rhizobium sp]] | + | [[Category: Rhizobium sp. MTP-10005]] |
| - | [[Category: Goto | + | [[Category: Goto M]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of 2,6-Dihydroxybenzoate Decarboxylase Complexed with inhibitor 2,3-dihydroxybenzaldehyde
| |||||||||||
