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2e4m

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Current revision (08:34, 25 October 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2e4m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4M FirstGlance]. <br>
<table><tr><td colspan='2'>[[2e4m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4M FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4m OCA], [https://pdbe.org/2e4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4m RCSB], [https://www.ebi.ac.uk/pdbsum/2e4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4m ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4m OCA], [https://pdbe.org/2e4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4m RCSB], [https://www.ebi.ac.uk/pdbsum/2e4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/HA33_CLOBO HA33_CLOBO]] Protects the structural integrity of the neurotoxin; may increase internalization of the neurotoxin into the bloodstream of the host. Involved in binding to the small intestine through interactions with glycolipids and glycoproteins containing sialic acid moieties.
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[https://www.uniprot.org/uniprot/K4Q2R6_CLOBO K4Q2R6_CLOBO]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hasegawa, K]]
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[[Category: Hasegawa K]]
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[[Category: Niwa, K]]
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[[Category: Niwa K]]
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[[Category: Ohyama, T]]
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[[Category: Ohyama T]]
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[[Category: Suzuki, T]]
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[[Category: Suzuki T]]
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[[Category: Watanabe, T]]
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[[Category: Watanabe T]]
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[[Category: Yamano, A]]
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[[Category: Yamano A]]
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[[Category: Botulinum toxin]]
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[[Category: Hemagglutinin subcomponent complex]]
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[[Category: Toxin]]
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Current revision

Crystal structure of hemagglutinin subcomponent complex (HA-33/HA-17) from Clostridium botulinum serotype D strain 4947

PDB ID 2e4m

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