2e6a
From Proteopedia
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<StructureSection load='2e6a' size='340' side='right'caption='[[2e6a]], [[Resolution|resolution]] 1.64Å' scene=''> | <StructureSection load='2e6a' size='340' side='right'caption='[[2e6a]], [[Resolution|resolution]] 1.64Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e6a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e6a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6A FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6a OCA], [https://pdbe.org/2e6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6a RCSB], [https://www.ebi.ac.uk/pdbsum/2e6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6a ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6a OCA], [https://pdbe.org/2e6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6a RCSB], [https://www.ebi.ac.uk/pdbsum/2e6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6a ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma cruzi]] |
| - | [[Category: Aoki | + | [[Category: Aoki T]] |
| - | [[Category: Harada | + | [[Category: Harada S]] |
| - | [[Category: Inaoka | + | [[Category: Inaoka DK]] |
| - | [[Category: Kita | + | [[Category: Kita K]] |
| - | [[Category: Kurisu | + | [[Category: Kurisu G]] |
| - | [[Category: Nara | + | [[Category: Nara T]] |
| - | [[Category: Sakamoto | + | [[Category: Sakamoto K]] |
| - | [[Category: Shiba | + | [[Category: Shiba T]] |
| - | [[Category: Shimizu | + | [[Category: Shimizu H]] |
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Revision as of 08:35, 25 October 2023
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with orotate
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Categories: Large Structures | Trypanosoma cruzi | Aoki T | Harada S | Inaoka DK | Kita K | Kurisu G | Nara T | Sakamoto K | Shiba T | Shimizu H
