2eh8

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<StructureSection load='2eh8' size='340' side='right'caption='[[2eh8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='2eh8' size='340' side='right'caption='[[2eh8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2eh8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EH8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2eh8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_B_virus Hepatitis B virus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EH8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EH8 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2eh7|2eh7]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HUMANIZED KR127 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eh8 OCA], [https://pdbe.org/2eh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eh8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eh8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eh8 OCA], [https://pdbe.org/2eh8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eh8 RCSB], [https://www.ebi.ac.uk/pdbsum/2eh8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eh8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q2EID8_HBV Q2EID8_HBV]] The middle envelope protein plays an important role in the budding of the virion. It is involved in the induction of budding in a nucleocapsid independent way. In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid (By similarity).[SAAS:SAAS000349_004_055156]
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[https://www.uniprot.org/uniprot/Q2EID8_HBV Q2EID8_HBV] The middle envelope protein plays an important role in the budding of the virion. It is involved in the induction of budding in a nucleocapsid independent way. In this process the majority of envelope proteins bud to form subviral lipoprotein particles of 22 nm of diameter that do not contain a nucleocapsid (By similarity).[SAAS:SAAS000349_004_055156]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hepatitis B virus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Chi, S W]]
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[[Category: Chi S-W]]
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[[Category: Hong, H J]]
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[[Category: Hong HJ]]
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[[Category: Kim, S J]]
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[[Category: Kim S-J]]
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[[Category: Maeng, C Y]]
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[[Category: Maeng C-Y]]
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[[Category: Ryu, S E]]
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[[Category: Ryu S-E]]
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[[Category: Hepatitis b virus]]
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[[Category: Humanized antibody]]
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[[Category: Immune system]]
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[[Category: Monoclonal antibody]]
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[[Category: Neutralization]]
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[[Category: Pres1]]
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Revision as of 08:40, 25 October 2023

Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope

PDB ID 2eh8

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