2f0z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:44, 25 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2f0z' size='340' side='right'caption='[[2f0z]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2f0z' size='340' side='right'caption='[[2f0z]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2f0z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0Z FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2f0z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F0Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F0Z FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZMR:ZANAMIVIR'>ZMR</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1snt|1snt]], [[1so7|1so7]], [[1vcu|1vcu]], [[2f10|2f10]], [[2f11|2f11]], [[2f12|2f12]], [[2f13|2f13]], [[2f24|2f24]], [[2f25|2f25]], [[2f26|2f26]], [[2f27|2f27]], [[2f28|2f28]], [[2f29|2f29]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZMR:ZANAMIVIR'>ZMR</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0z OCA], [https://pdbe.org/2f0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0z RCSB], [https://www.ebi.ac.uk/pdbsum/2f0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f0z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f0z OCA], [https://pdbe.org/2f0z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f0z RCSB], [https://www.ebi.ac.uk/pdbsum/2f0z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f0z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN]] Hydrolyzes sialylated compounds.
+
[https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 26: Line 25:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Exo-alpha-sialidase]]
+
[[Category: Homo sapiens]]
-
[[Category: Human]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Chavas, L M.G]]
+
[[Category: Chavas LMG]]
-
[[Category: Colman, P M]]
+
[[Category: Colman PM]]
-
[[Category: Fusi, P]]
+
[[Category: Fusi P]]
-
[[Category: Kato, R]]
+
[[Category: Kato R]]
-
[[Category: McKimm-Breschkin, J]]
+
[[Category: McKimm-Breschkin J]]
-
[[Category: Monti, E]]
+
[[Category: Monti E]]
-
[[Category: Tettamanti, G]]
+
[[Category: Tettamanti G]]
-
[[Category: Tringali, C]]
+
[[Category: Tringali C]]
-
[[Category: Venerando, B]]
+
[[Category: Venerando B]]
-
[[Category: Wakatsuki, S]]
+
[[Category: Wakatsuki S]]
-
[[Category: Hydrolase]]
+
-
[[Category: Influenza virus]]
+
-
[[Category: Neuraminidase]]
+
-
[[Category: Sialidase]]
+
-
[[Category: Zanamivir]]
+

Current revision

Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor

PDB ID 2f0z

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools