2ywc

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<StructureSection load='2ywc' size='340' side='right'caption='[[2ywc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2ywc' size='340' side='right'caption='[[2ywc]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ywc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YWC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ywc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YWC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ywb|2ywb]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">guaA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywc OCA], [https://pdbe.org/2ywc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ywc RCSB], [https://www.ebi.ac.uk/pdbsum/2ywc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ywc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ywc TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ywc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ywc OCA], [https://pdbe.org/2ywc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ywc RCSB], [https://www.ebi.ac.uk/pdbsum/2ywc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ywc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ywc TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/GUAA_THET8 GUAA_THET8]] Catalyzes the synthesis of GMP from XMP (By similarity).
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[https://www.uniprot.org/uniprot/GUAA_THET8 GUAA_THET8] Catalyzes the synthesis of GMP from XMP (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thet8]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Baba, S]]
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[[Category: Baba S]]
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[[Category: Kanagawa, M]]
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[[Category: Kanagawa M]]
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[[Category: Kawai, G]]
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[[Category: Kawai G]]
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[[Category: Kuramitsu, S]]
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[[Category: Kuramitsu S]]
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[[Category: Structural genomic]]
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[[Category: Sampei G]]
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[[Category: Sampei, G]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Atp binding]]
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[[Category: Gmp synthetase]]
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[[Category: Ligase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Purine nucleotide biosynthetic pathway]]
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[[Category: Rsgi]]
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[[Category: Xmp binding]]
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Revision as of 09:07, 25 October 2023

Crystal structure of GMP synthetase from Thermus thermophilus in complex with XMP

PDB ID 2ywc

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