7tq4

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7tq4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[7tq4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TQ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TQ4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IRZ:N~2~-({[(1R,2R)-2-(3-chlorophenyl)cyclopropyl]methoxy}carbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide'>IRZ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IRZ:N~2~-({[(1R,2R)-2-(3-chlorophenyl)cyclopropyl]methoxy}carbonyl)-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide'>IRZ</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq4 OCA], [https://pdbe.org/7tq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq4 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq4 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tq4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tq4 OCA], [https://pdbe.org/7tq4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tq4 RCSB], [https://www.ebi.ac.uk/pdbsum/7tq4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tq4 ProSAT]</span></td></tr>
</table>
</table>

Revision as of 09:47, 25 October 2023

Structure of SARS-CoV-2 3CL protease in complex with the cyclopropane based inhibitor 6c

PDB ID 7tq4

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