7xt0

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'''Unreleased structure'''
 
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The entry 7xt0 is ON HOLD until Paper Publication
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==Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors==
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<StructureSection load='7xt0' size='340' side='right'caption='[[7xt0]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
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Authors: Wang, D.P., Jiang, F.Y., Zeng, X.Y., Zhao, R., Chen, C., Zhu, Y., Cao, J.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xt0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saint_Louis_encephalitis_virus Saint Louis encephalitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XT0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XT0 FirstGlance]. <br>
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Description: Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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[[Category: Zhao, R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xt0 OCA], [https://pdbe.org/7xt0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xt0 RCSB], [https://www.ebi.ac.uk/pdbsum/7xt0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xt0 ProSAT]</span></td></tr>
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[[Category: Jiang, F.Y]]
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</table>
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[[Category: Wang, D.P]]
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== Function ==
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[[Category: Zhu, Y]]
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[https://www.uniprot.org/uniprot/A0A6M5UNY4_9FLAV A0A6M5UNY4_9FLAV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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[[Category: Chen, C]]
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__TOC__
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[[Category: Zeng, X.Y]]
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</StructureSection>
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[[Category: Cao, J.M]]
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[[Category: Large Structures]]
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[[Category: Saint Louis encephalitis virus]]
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[[Category: Cao JM]]
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[[Category: Chen C]]
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[[Category: Jiang FY]]
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[[Category: Wang DP]]
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[[Category: Zeng XY]]
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[[Category: Zhao R]]
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[[Category: Zhu Y]]

Revision as of 13:01, 1 November 2023

Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors

PDB ID 7xt0

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OCA

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