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2zpp
From Proteopedia
(Difference between revisions)
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2zpp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPP FirstGlance]. <br> | <table><tr><td colspan='2'>[[2zpp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZPP FirstGlance]. <br> | ||
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Neutron Diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DOD:DEUTERATED+WATER'>DOD</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpp OCA], [https://pdbe.org/2zpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpp RCSB], [https://www.ebi.ac.uk/pdbsum/2zpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zpp OCA], [https://pdbe.org/2zpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zpp RCSB], [https://www.ebi.ac.uk/pdbsum/2zpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zpp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/INS_PIG INS_PIG] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Ishikawa | + | [[Category: Ishikawa T]] |
| - | [[Category: Niimura | + | [[Category: Niimura N]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka I]] |
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Current revision
Neutron crystal structure of cubic insulin at pD9
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