2zsu

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Current revision (13:53, 1 November 2023) (edit) (undo)
 
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<StructureSection load='2zsu' size='340' side='right'caption='[[2zsu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2zsu' size='340' side='right'caption='[[2zsu]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zsu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/'pyrococcus_shinkaii' 'pyrococcus shinkaii']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZSU OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ZSU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zsu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZSU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AG3:1-{4-[(3-AMINOPROPYL)AMINO]BUTYL}GUANIDINE'>AG3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Spermidine_synthase Spermidine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.16 2.5.1.16] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AG3:1-{4-[(3-AMINOPROPYL)AMINO]BUTYL}GUANIDINE'>AG3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2zsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zsu OCA], [http://pdbe.org/2zsu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2zsu RCSB], [http://www.ebi.ac.uk/pdbsum/2zsu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2zsu ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zsu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zsu OCA], [https://pdbe.org/2zsu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zsu RCSB], [https://www.ebi.ac.uk/pdbsum/2zsu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zsu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPEE_PYRHO SPEE_PYRHO]] Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine (By similarity).[HAMAP-Rule:MF_00198]
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[https://www.uniprot.org/uniprot/SPEE_PYRHO SPEE_PYRHO] Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine (By similarity).[HAMAP-Rule:MF_00198]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pyrococcus shinkaii]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Spermidine synthase]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Kunishima, N]]
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[[Category: Kunishima N]]
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[[Category: Mizutani, H]]
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[[Category: Mizutani H]]
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[[Category: Aminopropylagmatine]]
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[[Category: Polyamine biosynthesis]]
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[[Category: Spermidine biosynthesis]]
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[[Category: Transferase]]
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Current revision

Crystal structure of spermidine synthase from Pyrococcus horikoshii OT3, P1 form

PDB ID 2zsu

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