2zwm

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Current revision (13:59, 1 November 2023) (edit) (undo)
 
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<StructureSection load='2zwm' size='340' side='right'caption='[[2zwm]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
<StructureSection load='2zwm' size='340' side='right'caption='[[2zwm]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2zwm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZWM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2zwm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZWM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2d1v|2d1v]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">yycF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zwm OCA], [https://pdbe.org/2zwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zwm RCSB], [https://www.ebi.ac.uk/pdbsum/2zwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zwm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zwm OCA], [https://pdbe.org/2zwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zwm RCSB], [https://www.ebi.ac.uk/pdbsum/2zwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zwm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/YYCF_BACSU YYCF_BACSU]] Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter sequence in vitro. YycF has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA.<ref>PMID:9829949</ref> <ref>PMID:10878122</ref> <ref>PMID:17581128</ref>
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[https://www.uniprot.org/uniprot/WALR_BACSU WALR_BACSU] Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA.<ref>PMID:10878122</ref> <ref>PMID:12950927</ref> <ref>PMID:17581128</ref> <ref>PMID:9829949</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Vibrio subtilis ehrenberg 1835]]
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[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Doi, A]]
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[[Category: Doi A]]
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[[Category: Okajima, T]]
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[[Category: Okajima T]]
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[[Category: Utsumi, R]]
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[[Category: Utsumi R]]
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[[Category: Cytoplasm]]
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[[Category: Dimerization domain]]
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[[Category: Dna-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation site]]
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[[Category: Response regulator]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Two-component regulatory system]]
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[[Category: Two-component system]]
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Current revision

Crystal structure of YycF receiver domain from Bacillus subtilis

PDB ID 2zwm

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