3a65

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Current revision (14:13, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3a65' size='340' side='right'caption='[[3a65]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3a65' size='340' side='right'caption='[[3a65]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3a65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Flask Flask]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A65 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3a65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paenarthrobacter_ureafaciens Paenarthrobacter ureafaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A65 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACA:6-AMINOHEXANOIC+ACID'>ACA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1wyb|1wyb]], [[1wyc|1wyc]], [[2dcf|2dcf]], [[2zm0|2zm0]], [[2zma|2zma]], [[3a66|3a66]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACA:6-AMINOHEXANOIC+ACID'>ACA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nylB, NYLB' ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261 FLASK])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/6-aminohexanoate-dimer_hydrolase 6-aminohexanoate-dimer hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.46 3.5.1.46] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a65 OCA], [https://pdbe.org/3a65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a65 RCSB], [https://www.ebi.ac.uk/pdbsum/3a65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a65 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a65 OCA], [https://pdbe.org/3a65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a65 RCSB], [https://www.ebi.ac.uk/pdbsum/3a65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a65 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NYLB2_FLASK NYLB2_FLASK] Involved in nylon oligomer degradation.<ref>PMID:6389532</ref> <ref>PMID:6646204</ref> [https://www.uniprot.org/uniprot/NYLB_FLASK NYLB_FLASK]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[6-aminohexanoate-dimer hydrolase 3D structures|6-aminohexanoate-dimer hydrolase 3D structures]]
*[[6-aminohexanoate-dimer hydrolase 3D structures|6-aminohexanoate-dimer hydrolase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-aminohexanoate-dimer hydrolase]]
 
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[[Category: Flask]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Higuchi, Y]]
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[[Category: Paenarthrobacter ureafaciens]]
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[[Category: Kawashima, Y]]
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[[Category: Higuchi Y]]
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[[Category: Negoro, S]]
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[[Category: Kawashima Y]]
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[[Category: Shibata, N]]
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[[Category: Negoro S]]
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[[Category: Takeo, M]]
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[[Category: Shibata N]]
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[[Category: Hydrolase]]
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[[Category: Takeo M]]
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[[Category: Nylon degradation]]
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Current revision

Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/H266N mutant with substrate

PDB ID 3a65

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