3adp

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Current revision (14:20, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3adp' size='340' side='right'caption='[[3adp]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
<StructureSection load='3adp' size='340' side='right'caption='[[3adp]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3adp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/European_rabbit European rabbit]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3a97 3a97] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ep9 2ep9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ADP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3adp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3a97 3a97] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ep9 2ep9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ADP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ADP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ado|3ado]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYL1, GUL3DH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-gulonate_3-dehydrogenase L-gulonate 3-dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.45 1.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3adp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3adp OCA], [https://pdbe.org/3adp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3adp RCSB], [https://www.ebi.ac.uk/pdbsum/3adp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3adp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3adp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3adp OCA], [https://pdbe.org/3adp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3adp RCSB], [https://www.ebi.ac.uk/pdbsum/3adp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3adp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT]] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.
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[https://www.uniprot.org/uniprot/CRYL1_RABIT CRYL1_RABIT] Functions as crystallin in the rabbit eye lens. Has high L-gulonate 3-dehydrogenase activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: European rabbit]]
 
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[[Category: L-gulonate 3-dehydrogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Asada, Y]]
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[[Category: Oryctolagus cuniculus]]
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[[Category: Hara, A]]
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[[Category: Asada Y]]
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[[Category: Kunishima, N]]
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[[Category: Hara A]]
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[[Category: Structural genomic]]
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[[Category: Kunishima N]]
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[[Category: Acetylation]]
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[[Category: Cytoplasm]]
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[[Category: Eye lens protein]]
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[[Category: Nad]]
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[[Category: Oxidoreductase]]
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[[Category: Rsgi]]
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Current revision

Crystal Structure of the Rabbit L-Gulonate 3-Dehydrogenase (NADH Form)

PDB ID 3adp

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