3cxa
From Proteopedia
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<StructureSection load='3cxa' size='340' side='right'caption='[[3cxa]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='3cxa' size='340' side='right'caption='[[3cxa]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3cxa]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3cxa]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CXA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900006:trehalose'>PRD_900006</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxa OCA], [https://pdbe.org/3cxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cxa RCSB], [https://www.ebi.ac.uk/pdbsum/3cxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxa ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PGRP1_CAMDR PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Camelus dromedarius]] | [[Category: Camelus dromedarius]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Balaji | + | [[Category: Balaji K]] |
| - | [[Category: Bhushan | + | [[Category: Bhushan A]] |
| - | [[Category: Kaur | + | [[Category: Kaur P]] |
| - | [[Category: Sharma | + | [[Category: Sharma P]] |
| - | [[Category: Sharma | + | [[Category: Sharma S]] |
| - | [[Category: Singh | + | [[Category: Singh N]] |
| - | [[Category: Singh | + | [[Category: Singh TP]] |
| - | [[Category: Sinha | + | [[Category: Sinha M]] |
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Revision as of 15:00, 1 November 2023
Crystal structure of the complex of peptidoglycan recognition protein with alpha-D-glucopyranosyl alpha-D-glucopyranoside at 3.4 A resolution
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Categories: Camelus dromedarius | Large Structures | Balaji K | Bhushan A | Kaur P | Sharma P | Sharma S | Singh N | Singh TP | Sinha M
