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1nxi

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[[Image:1nxi.gif|left|200px]]
[[Image:1nxi.gif|left|200px]]
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{{Structure
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|GENE= VC0424 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK11191 PRK11191]</span>
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{{STRUCTURE_1nxi| PDB=1nxi | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxi OCA], [http://www.ebi.ac.uk/pdbsum/1nxi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nxi RCSB]</span>
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'''Solution structure of Vibrio cholerae protein VC0424'''
'''Solution structure of Vibrio cholerae protein VC0424'''
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[[Category: Ni, S.]]
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[[Category: Ab sandwich]]
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[[Category: atcc no. 51394d]]
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[[Category: Atcc no. 51394d]]
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[[Category: cog 3076]]
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[[Category: Cog 3076]]
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[[Category: nesg target op3]]
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[[Category: Nesg target op3]]
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[[Category: northeast structural genomics consortium]]
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Revision as of 00:05, 3 May 2008

Image:1nxi.gif

Template:STRUCTURE 1nxi

Solution structure of Vibrio cholerae protein VC0424


Overview

The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins.

About this Structure

1NXI is a Single protein structure of sequence from Vibrio cholerae. Full crystallographic information is available from OCA.

Reference

Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold., Ramelot TA, Ni S, Goldsmith-Fischman S, Cort JR, Honig B, Kennedy MA, Protein Sci. 2003 Jul;12(7):1556-61. PMID:12824501 Page seeded by OCA on Sat May 3 03:05:51 2008

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