3gr8

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Current revision (15:44, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3gr8' size='340' side='right'caption='[[3gr8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3gr8' size='340' side='right'caption='[[3gr8]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3gr8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_kaustophilus"_prickett_1928 "bacillus kaustophilus" prickett 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GR8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3gr8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_kaustophilus Geobacillus kaustophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GR8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gr7|3gr7]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">namA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1462 "Bacillus kaustophilus" Prickett 1928])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NADPH_dehydrogenase NADPH dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.99.1 1.6.99.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gr8 OCA], [https://pdbe.org/3gr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gr8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gr8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gr8 OCA], [https://pdbe.org/3gr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gr8 RCSB], [https://www.ebi.ac.uk/pdbsum/3gr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gr8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NAMA_GEOKA NAMA_GEOKA]] Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes (By similarity).
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[https://www.uniprot.org/uniprot/NAMA_GEOKA NAMA_GEOKA] Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus kaustophilus prickett 1928]]
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[[Category: Geobacillus kaustophilus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: NADPH dehydrogenase]]
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[[Category: Gruber K]]
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[[Category: Gruber, K]]
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[[Category: Uhl MK]]
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[[Category: Uhl, M K]]
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[[Category: Beta-alpha-barrel]]
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[[Category: Flavin]]
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[[Category: Flavoprotein]]
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[[Category: Fmn]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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Current revision

Structure of OYE from Geobacillus kaustophilus, orthorhombic crystal form

PDB ID 3gr8

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