This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3lcf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:22, 1 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3lcf' size='340' side='right'caption='[[3lcf]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
<StructureSection load='3lcf' size='340' side='right'caption='[[3lcf]], [[Resolution|resolution]] 1.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3lcf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LCF FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3lcf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LCF FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nal|1nal]], [[3lbc|3lbc]], [[3lbm|3lbm]], [[3lcg|3lcg]], [[3lch|3lch]], [[3lci|3lci]], [[3lcl|3lcl]], [[3lcw|3lcw]], [[3lcx|3lcx]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b3225, JW3194, nanA, npl ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/N-acetylneuraminate_lyase N-acetylneuraminate lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.3 4.1.3.3] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lcf OCA], [https://pdbe.org/3lcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lcf RCSB], [https://www.ebi.ac.uk/pdbsum/3lcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lcf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lcf OCA], [https://pdbe.org/3lcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lcf RCSB], [https://www.ebi.ac.uk/pdbsum/3lcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lcf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI]] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]
+
[https://www.uniprot.org/uniprot/NANA_ECOLI NANA_ECOLI] Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate.[HAMAP-Rule:MF_01237]
==See Also==
==See Also==
-
*[[Aldolase 3D structures|Aldolase 3D structures]]
+
*[[N-acetylneuraminate lyase 3D structures|N-acetylneuraminate lyase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ecoli]]
+
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: N-acetylneuraminate lyase]]
+
[[Category: Chou C-Y]]
-
[[Category: Chou, C Y]]
+
[[Category: Ko T-P]]
-
[[Category: Ko, T P]]
+
[[Category: Wang AH-J]]
-
[[Category: Wang, A H.J]]
+
-
[[Category: Carbohydrate metabolism]]
+
-
[[Category: Lyase]]
+
-
[[Category: Schiff base]]
+
-
[[Category: Tim barrel]]
+

Current revision

The D-sialic acid aldolase mutant V251I

PDB ID 3lcf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools