3ml5

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Current revision (16:35, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3ml5' size='340' side='right'caption='[[3ml5]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='3ml5' size='340' side='right'caption='[[3ml5]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ml5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ML5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ML5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ml5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ML5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ML5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZM:5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>AZM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CA7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZM:5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE'>AZM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ml5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ml5 OCA], [https://pdbe.org/3ml5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ml5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ml5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ml5 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ml5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ml5 OCA], [https://pdbe.org/3ml5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ml5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ml5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ml5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAH7_HUMAN CAH7_HUMAN]] Reversible hydration of carbon dioxide.
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[https://www.uniprot.org/uniprot/CAH7_HUMAN CAH7_HUMAN] Reversible hydration of carbon dioxide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Carbonate dehydratase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Alterio, V]]
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[[Category: Alterio V]]
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[[Category: Bootorabi, F]]
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[[Category: Bootorabi F]]
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[[Category: Dathan, N]]
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[[Category: Dathan N]]
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[[Category: Fiore, A Di]]
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[[Category: De Simone G]]
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[[Category: Monti, S M]]
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[[Category: Di Fiore A]]
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[[Category: Parkkila, S]]
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[[Category: Monti SM]]
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[[Category: Simone, G De]]
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[[Category: Parkkila S]]
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[[Category: Supuran, C T]]
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[[Category: Supuran CT]]
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[[Category: Truppo, E]]
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[[Category: Truppo E]]
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[[Category: Lyase]]
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[[Category: Protein-inhibitor complex]]
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Current revision

Crystal structure of the C183S/C217S mutant of human CA VII in complex with acetazolamide

PDB ID 3ml5

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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