3pl1

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Current revision (17:06, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3pl1' size='340' side='right'caption='[[3pl1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3pl1' size='340' side='right'caption='[[3pl1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3gbc 3gbc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PL1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pl1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3gbc 3gbc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PL1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2103, pncA, Rv2043c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.19 3.5.1.19] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pl1 OCA], [https://pdbe.org/3pl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3pl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pl1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pl1 OCA], [https://pdbe.org/3pl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pl1 RCSB], [https://www.ebi.ac.uk/pdbsum/3pl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pl1 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q50575_MYCTX Q50575_MYCTX]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hydrolase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Gelus-Ziental, N]]
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[[Category: Gelus-Ziental N]]
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[[Category: Mayer, C]]
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[[Category: Mayer C]]
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[[Category: Petrella, S]]
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[[Category: Petrella S]]
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[[Category: Sougakoff, W]]
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[[Category: Sougakoff W]]
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[[Category: Nicotinamidase-pyrazinamidase]]
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[[Category: Resistance to pyrazinamide]]
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[[Category: Rossmann fold]]
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Current revision

Determination of the crystal structure of the pyrazinamidase from M.tuberculosis : a structure-function analysis for prediction resistance to pyrazinamide.

PDB ID 3pl1

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OCA

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