3s9a

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Current revision (17:23, 1 November 2023) (edit) (undo)
 
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<StructureSection load='3s9a' size='340' side='right'caption='[[3s9a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='3s9a' size='340' side='right'caption='[[3s9a]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Daboia_russellii_siamensis Daboia russellii siamensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S9A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Daboia_siamensis Daboia siamensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S9A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3s9b|3s9b]], [[3s9c|3s9c]], [[3sbk|3sbk]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Snake_venom_factor_V_activator Snake venom factor V activator], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.95 3.4.21.95] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9a OCA], [https://pdbe.org/3s9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9a RCSB], [https://www.ebi.ac.uk/pdbsum/3s9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s9a OCA], [https://pdbe.org/3s9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s9a RCSB], [https://www.ebi.ac.uk/pdbsum/3s9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s9a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VSPG_DABSI VSPG_DABSI]] Venom serine protease that selectively activates factor V (F5) in a calcium-independent manner. It cleaves the Arg(1545)-Ser(1546) linkage in the human factor V molecule. Induces the coagulation of mammalian plasma.<ref>PMID:3053712</ref>
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[https://www.uniprot.org/uniprot/VSPG_DABSI VSPG_DABSI] Venom serine protease that selectively activates factor V (F5) in a calcium-independent manner. It cleaves the Arg(1545)-Ser(1546) linkage in the human factor V molecule. Induces the coagulation of mammalian plasma.<ref>PMID:3053712</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Daboia russellii siamensis]]
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[[Category: Daboia siamensis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Snake venom factor V activator]]
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[[Category: Ben Ammar Y]]
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[[Category: Ammar, Y Ben]]
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[[Category: Nakayama D]]
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[[Category: Nakayama, D]]
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[[Category: Takeda S]]
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[[Category: Takeda, S]]
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[[Category: Double six-stranded beta-barrel]]
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[[Category: Glycosylation]]
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[[Category: Hydrolase]]
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[[Category: Serine proteinase]]
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Current revision

Russell's viper venom serine proteinase, RVV-V (closed-form)

PDB ID 3s9a

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