2kgp

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==Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)==
==Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)==
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<StructureSection load='2kgp' size='340' side='right'caption='[[2kgp]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='2kgp' size='340' side='right'caption='[[2kgp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kgp]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KGP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kgp]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KGP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KGP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MIX:1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE'>MIX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MIX:1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE'>MIX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kgp OCA], [https://pdbe.org/2kgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kgp RCSB], [https://www.ebi.ac.uk/pdbsum/2kgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kgp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kgp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kgp OCA], [https://pdbe.org/2kgp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kgp RCSB], [https://www.ebi.ac.uk/pdbsum/2kgp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kgp ProSAT]</span></td></tr>
</table>
</table>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Chen, Y]]
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[[Category: Chen Y]]
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[[Category: Donahue, C P]]
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[[Category: Donahue CP]]
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[[Category: Varani, G]]
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[[Category: Varani G]]
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[[Category: Wolfe, M S]]
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[[Category: Wolfe MS]]
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[[Category: Zheng, S]]
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[[Category: Zheng S]]
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[[Category: Mitoxantrone]]
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[[Category: Novantrone]]
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[[Category: Rna]]
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[[Category: Rna-small molecule]]
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[[Category: Splicing regulatory element]]
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[[Category: Tau pre-mrna]]
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[[Category: Tauopathy]]
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Revision as of 18:08, 1 November 2023

Structural basis for stabilization of the tau pre-mRNA splicing regulatory element by Novantrone (Mitoxantrone)

PDB ID 2kgp

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