5m4x

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Current revision (18:26, 1 November 2023) (edit) (undo)
 
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<StructureSection load='5m4x' size='340' side='right'caption='[[5m4x]], [[Resolution|resolution]] 3.56&Aring;' scene=''>
<StructureSection load='5m4x' size='340' side='right'caption='[[5m4x]], [[Resolution|resolution]] 3.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5m4x]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M4X OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5M4X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5m4x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum_DSM_1728 Thermoplasma acidophilum DSM 1728]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M4X FirstGlance]. <br>
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</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/D-glyceraldehyde_dehydrogenase_(NADP(+)) D-glyceraldehyde dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.89 1.2.1.89] </span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.56&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5m4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m4x OCA], [http://pdbe.org/5m4x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m4x RCSB], [http://www.ebi.ac.uk/pdbsum/5m4x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m4x ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m4x OCA], [https://pdbe.org/5m4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m4x RCSB], [https://www.ebi.ac.uk/pdbsum/5m4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m4x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GADH_THEAC GADH_THEAC]] NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.<ref>PMID:16458304</ref> <ref>PMID:16566751</ref>
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[https://www.uniprot.org/uniprot/GADH_THEAC GADH_THEAC] NADP-dependent dehydrogenase of the nED (non-phosphorylated Entner-Doudoroff) pathway with highest activity towards glyceraldehydes (e.g. D,L-glyceraldehyde and D-glyceraldehyde), to a lesser extent towards D,L-glyceraldehyde-3-phosphate and glycolaldehyde, but no activity towards aliphatic or aromatic aldehydes.<ref>PMID:16458304</ref> <ref>PMID:16566751</ref>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Iermak, I]]
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[[Category: Thermoplasma acidophilum DSM 1728]]
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[[Category: Mesters, J R]]
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[[Category: Iermak I]]
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[[Category: Smatanova, I Kuta]]
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[[Category: Kuta Smatanova I]]
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[[Category: Oxidoreductase]]
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[[Category: Mesters JR]]

Current revision

Mutant glyceraldehyde dehydrogenase (F34M+Y399C+S405N) from Thermoplasma acidophilum

PDB ID 5m4x

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