This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5mcp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:38, 1 November 2023) (edit) (undo)
 
Line 1: Line 1:
==Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP==
==Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP==
-
<StructureSection load='5mcp' size='340' side='right' caption='[[5mcp]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
+
<StructureSection load='5mcp' size='340' side='right'caption='[[5mcp]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5mcp]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ashgo Ashgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MCP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MCP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5mcp]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Eremothecium_gossypii_ATCC_10895 Eremothecium gossypii ATCC 10895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MCP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4z87|4z87]], [[5tc3|5tc3]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AGOS_AER117W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284811 ASHGO])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mcp OCA], [https://pdbe.org/5mcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mcp RCSB], [https://www.ebi.ac.uk/pdbsum/5mcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mcp ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mcp OCA], [http://pdbe.org/5mcp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mcp RCSB], [http://www.ebi.ac.uk/pdbsum/5mcp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mcp ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/Q756Z6_ASHGO Q756Z6_ASHGO]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_03156]
+
[https://www.uniprot.org/uniprot/Q756Z6_ASHGO Q756Z6_ASHGO] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_03156]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 19:
</div>
</div>
<div class="pdbe-citations 5mcp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mcp" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ashgo]]
+
[[Category: Eremothecium gossypii ATCC 10895]]
-
[[Category: IMP dehydrogenase]]
+
[[Category: Large Structures]]
-
[[Category: Buey, R M]]
+
[[Category: Buey RM]]
-
[[Category: Fernandez-Justel, D]]
+
[[Category: Fernandez-Justel D]]
-
[[Category: Pereda, J M.de]]
+
[[Category: Revuelta JL]]
-
[[Category: Revuelta, J L]]
+
[[Category: Winter G]]
-
[[Category: Winter, G]]
+
[[Category: De Pereda JM]]
-
[[Category: Allosteric modulator]]
+
-
[[Category: Ashbya gossypii]]
+
-
[[Category: Imp dehydrogenase]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: Purine nucleotide]]
+

Current revision

Structure of IMP dehydrogenase from Ashbya gossypii bound to ATP

PDB ID 5mcp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5mcp"
Personal tools