3vma

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Current revision (12:26, 8 November 2023) (edit) (undo)
 
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<StructureSection load='3vma' size='340' side='right'caption='[[3vma]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
<StructureSection load='3vma' size='340' side='right'caption='[[3vma]], [[Resolution|resolution]] 2.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vma]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3fwm 3fwm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vma]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3fwm 3fwm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VMA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M0E:MOENOMYCIN'>M0E</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.161&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3fwl|3fwl]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M0E:MOENOMYCIN'>M0E</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b0149, JW0145, mrcB, pbpF, ponB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vma OCA], [https://pdbe.org/3vma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vma RCSB], [https://www.ebi.ac.uk/pdbsum/3vma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vma ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vma OCA], [https://pdbe.org/3vma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vma RCSB], [https://www.ebi.ac.uk/pdbsum/3vma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vma ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PBPB_ECOLI PBPB_ECOLI]] Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
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[https://www.uniprot.org/uniprot/PBPB_ECOLI PBPB_ECOLI] Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cheng, W C]]
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[[Category: Cheng WC]]
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[[Category: Chou, L Y]]
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[[Category: Chou LY]]
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[[Category: Huang, C Y]]
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[[Category: Huang CY]]
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[[Category: Lai, Y T]]
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[[Category: Lai YT]]
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[[Category: Ma, C]]
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[[Category: Ma C]]
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[[Category: Shih, H W]]
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[[Category: Shih HW]]
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[[Category: Sung, M T]]
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[[Category: Sung MT]]
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[[Category: Wong, C H]]
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[[Category: Wong CH]]
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[[Category: Antibiotics design]]
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[[Category: Bacterial cell wall synthesis]]
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[[Category: Ftsn]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Membrane]]
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[[Category: Mipa]]
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[[Category: Mlta]]
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[[Category: Pbp3]]
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[[Category: Penicillin-binding protein]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli

PDB ID 3vma

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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