3vyn

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Current revision (12:42, 8 November 2023) (edit) (undo)
 
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<StructureSection load='3vyn' size='340' side='right'caption='[[3vyn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3vyn' size='340' side='right'caption='[[3vyn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYN FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vyo|3vyo]], [[3vyp|3vyp]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2518c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidyltransferase Peptidyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.12 2.3.2.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyn OCA], [https://pdbe.org/3vyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyn RCSB], [https://www.ebi.ac.uk/pdbsum/3vyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyn OCA], [https://pdbe.org/3vyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyn RCSB], [https://www.ebi.ac.uk/pdbsum/3vyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDT2_MYCTU LDT2_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.<ref>PMID:24041897</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidyltransferase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Bi, L J]]
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[[Category: Bi LJ]]
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[[Category: Li, D F]]
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[[Category: Li DF]]
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[[Category: Li, W J]]
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[[Category: Li WJ]]
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[[Category: Wang, D C]]
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[[Category: Wang DC]]
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[[Category: Beta barrel]]
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[[Category: Beta-lactam binding]]
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[[Category: D-transpeptidase]]
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[[Category: Transferase]]
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[[Category: Ykud domain]]
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Current revision

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2 N55 truncation mutant (resideus 55-408)

PDB ID 3vyn

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