3wsb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:25, 8 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3wsb' size='340' side='right'caption='[[3wsb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='3wsb' size='340' side='right'caption='[[3wsb]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wsb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wsb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wsa|3wsa]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPS:S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL]+TRIHYDROGEN+THIODIPHOSPHATE'>FPS</scene>, <scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tc00.1047053508369.20 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsb OCA], [https://pdbe.org/3wsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsb RCSB], [https://www.ebi.ac.uk/pdbsum/3wsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsb OCA], [https://pdbe.org/3wsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsb RCSB], [https://www.ebi.ac.uk/pdbsum/3wsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsb ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q4CWB4_TRYCC Q4CWB4_TRYCC]
==See Also==
==See Also==
Line 16: Line 16:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Squalene synthase]]
+
[[Category: Trypanosoma cruzi strain CL Brener]]
-
[[Category: Trycc]]
+
[[Category: Guo RT]]
-
[[Category: Guo, R T]]
+
[[Category: Huang CH]]
-
[[Category: Huang, C H]]
+
[[Category: Li Q]]
-
[[Category: Li, Q]]
+
[[Category: Oldfield E]]
-
[[Category: Oldfield, E]]
+
[[Category: Shang N]]
-
[[Category: Shang, N]]
+
-
[[Category: Drug discovery]]
+
-
[[Category: Fspp]]
+
-
[[Category: Isoprenoid]]
+
-
[[Category: Sq109]]
+
-
[[Category: Transferase-transferase inhibitor complex]]
+
-
[[Category: Trypanosoma cruzi squalene synthase]]
+

Current revision

The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole

PDB ID 3wsb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools