3wsa

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Current revision (13:25, 8 November 2023) (edit) (undo)
 
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<StructureSection load='3wsa' size='340' side='right'caption='[[3wsa]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='3wsa' size='340' side='right'caption='[[3wsa]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wsa]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WSA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wsb|3wsb]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RWZ:N-[(2Z)-3,7-DIMETHYLOCTA-2,6-DIEN-1-YL]-N-[(1R,3S,5R,7R)-TRICYCLO[3.3.1.1~3,7~]DEC-2-YL]ETHANE-1,2-DIAMINE'>RWZ</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDFT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [https://pdbe.org/3wsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [https://www.ebi.ac.uk/pdbsum/3wsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wsa OCA], [https://pdbe.org/3wsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wsa RCSB], [https://www.ebi.ac.uk/pdbsum/3wsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wsa ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FDFT_HUMAN FDFT_HUMAN]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Squalene synthase]]
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[[Category: Guo RT]]
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[[Category: Guo, R T]]
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[[Category: Huang CH]]
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[[Category: Huang, C H]]
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[[Category: Li Q]]
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[[Category: Li, Q]]
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[[Category: Oldfield E]]
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[[Category: Oldfield, E]]
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[[Category: Shang N]]
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[[Category: Shang, N]]
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[[Category: Drug discovery]]
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[[Category: Human squalene synthase]]
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[[Category: Isoprenoid]]
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[[Category: Sq-109]]
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[[Category: Transferase]]
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The Tuberculosis Drug SQ109 Inhibits Trypanosoma cruzi Cell Proliferation and acts Synergistically with Posaconazole

PDB ID 3wsa

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