5v2w

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==Crystal structure of a LuxS from salmonella typhi==
==Crystal structure of a LuxS from salmonella typhi==
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<StructureSection load='5v2w' size='340' side='right' caption='[[5v2w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5v2w' size='340' side='right'caption='[[5v2w]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5v2w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhi"_schroeter_1886 "bacillus typhi" schroeter 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V2W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5V2W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5v2w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5V2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5V2W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5e68|5e68]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5v2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v2w OCA], [https://pdbe.org/5v2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5v2w RCSB], [https://www.ebi.ac.uk/pdbsum/5v2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5v2w ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">luxS, STY2943, t2714 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90370 "Bacillus typhi" Schroeter 1886])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/S-ribosylhomocysteine_lyase S-ribosylhomocysteine lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.21 4.4.1.21] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5v2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5v2w OCA], [http://pdbe.org/5v2w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5v2w RCSB], [http://www.ebi.ac.uk/pdbsum/5v2w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5v2w ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LUXS_SALTI LUXS_SALTI]] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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[https://www.uniprot.org/uniprot/LUXS_SALTI LUXS_SALTI] Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).[HAMAP-Rule:MF_00091]
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==See Also==
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*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus typhi schroeter 1886]]
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[[Category: Large Structures]]
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[[Category: S-ribosylhomocysteine lyase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhi]]
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[[Category: Arockisamy, A]]
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[[Category: Arockisamy A]]
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[[Category: Kumar, P Manoj]]
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[[Category: Manoj Kumar P]]
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[[Category: Perumal, P]]
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[[Category: Perumal P]]
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[[Category: Raina, R]]
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[[Category: Raina R]]
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[[Category: SundaraBaalaji, N]]
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[[Category: SundaraBaalaji N]]
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[[Category: Lux]]
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[[Category: Lyase]]
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[[Category: Quroum sensing protein]]
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[[Category: Salmonella typhi]]
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Current revision

Crystal structure of a LuxS from salmonella typhi

PDB ID 5v2w

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