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5wr6

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Current revision (16:51, 8 November 2023) (edit) (undo)
 
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<StructureSection load='5wr6' size='340' side='right'caption='[[5wr6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='5wr6' size='340' side='right'caption='[[5wr6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wr6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WR6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5WR6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wr6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WR6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WR6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NX6:N-[(BENZYLOXY)CARBONYL]-L-ASPARTIC+ACID'>NX6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wr5|5wr5]], [[5wr4|5wr4]], [[5wr3|5wr3]], [[5wr2|5wr2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NX6:N-[(BENZYLOXY)CARBONYL]-L-ASPARTIC+ACID'>NX6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wr6 OCA], [https://pdbe.org/5wr6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wr6 RCSB], [https://www.ebi.ac.uk/pdbsum/5wr6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wr6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5wr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wr6 OCA], [http://pdbe.org/5wr6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wr6 RCSB], [http://www.ebi.ac.uk/pdbsum/5wr6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wr6 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_GEOSE THER_GEOSE]] Extracellular zinc metalloprotease.<ref>PMID:3149972</ref>
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[https://www.uniprot.org/uniprot/THER_GEOSE THER_GEOSE] Extracellular zinc metalloprotease.<ref>PMID:3149972</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Geobacillus stearothermophilus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Thermolysin]]
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[[Category: Kunishima N]]
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[[Category: Kunishima, N]]
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[[Category: Matsuura Y]]
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[[Category: Matsuura, Y]]
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[[Category: Naitow H]]
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[[Category: Naitow, H]]
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[[Category: Hydrolase]]
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[[Category: Microcrystal]]
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[[Category: Serial femtosecond crystallography]]
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[[Category: Structure-based drug design]]
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[[Category: X-ray free-electron laser]]
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Current revision

Thermolysin, liganded form with cryo condition 2

PDB ID 5wr6

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