This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5wsb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:52, 8 November 2023) (edit) (undo)
 
Line 1: Line 1:
==Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate==
==Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate==
-
<StructureSection load='5wsb' size='340' side='right' caption='[[5wsb]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
+
<StructureSection load='5wsb' size='340' side='right'caption='[[5wsb]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5wsb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WSB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WSB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5wsb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WSB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5wrp|5wrp]], [[5ws8|5ws8]], [[5ws9|5ws9]], [[5wsa|5wsa]], [[5wsc|5wsc]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyk, pykA, Rv1617, MTCY01B2.09 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wsb OCA], [https://pdbe.org/5wsb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wsb RCSB], [https://www.ebi.ac.uk/pdbsum/5wsb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wsb ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wsb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wsb OCA], [http://pdbe.org/5wsb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wsb RCSB], [http://www.ebi.ac.uk/pdbsum/5wsb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wsb ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KPYK_MYCTU KPYK_MYCTU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 19:
</div>
</div>
<div class="pdbe-citations 5wsb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5wsb" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Myctu]]
+
[[Category: Large Structures]]
-
[[Category: Pyruvate kinase]]
+
[[Category: Mycobacterium tuberculosis H37Rv]]
-
[[Category: Cai, Q]]
+
[[Category: Cai Q]]
-
[[Category: Dedon, P C]]
+
[[Category: Dedon PC]]
-
[[Category: Lescar, J]]
+
[[Category: El Sahili A]]
-
[[Category: Sahili, A El]]
+
[[Category: Lescar J]]
-
[[Category: Zhong, W]]
+
[[Category: Zhong W]]
-
[[Category: Allostery]]
+
-
[[Category: Glycolysis]]
+
-
[[Category: Phospho transferase]]
+
-
[[Category: Synergism]]
+
-
[[Category: Tetramer]]
+
-
[[Category: Transferase]]
+

Current revision

Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate

PDB ID 5wsb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5wsb"
Personal tools