2dla
From Proteopedia
(Difference between revisions)
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<StructureSection load='2dla' size='340' side='right'caption='[[2dla]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2dla' size='340' side='right'caption='[[2dla]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2dla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2dla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DLA FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dla OCA], [https://pdbe.org/2dla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dla RCSB], [https://www.ebi.ac.uk/pdbsum/2dla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dla ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dla OCA], [https://pdbe.org/2dla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dla RCSB], [https://www.ebi.ac.uk/pdbsum/2dla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dla ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/PRIL_PYRHO PRIL_PYRHO] Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.[HAMAP-Rule:MF_00701] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Pyrococcus horikoshii]] | + | [[Category: Pyrococcus horikoshii OT3]] |
- | [[Category: Ito | + | [[Category: Ito N]] |
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Revision as of 17:25, 8 November 2023
Primase large subunit amino terminal domain from Pyrococcus horikoshii
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