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5mlg

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Current revision (17:36, 8 November 2023) (edit) (undo)
 
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<StructureSection load='5mlg' size='340' side='right'caption='[[5mlg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5mlg' size='340' side='right'caption='[[5mlg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mlg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MLG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MLG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mlg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MLG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MLG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ren1, Ren ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mlg OCA], [https://pdbe.org/5mlg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mlg RCSB], [https://www.ebi.ac.uk/pdbsum/5mlg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mlg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mlg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mlg OCA], [http://pdbe.org/5mlg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mlg RCSB], [http://www.ebi.ac.uk/pdbsum/5mlg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mlg ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RENI_RAT RENI_RAT]] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
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[https://www.uniprot.org/uniprot/RENI_RAT RENI_RAT] Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Renin]]
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[[Category: Rattus norvegicus]]
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[[Category: Read, R]]
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[[Category: Read R]]
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[[Category: Yan, Y]]
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[[Category: Yan Y]]
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[[Category: Hydrolase]]
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[[Category: Prorenin]]
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[[Category: Rat]]
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Current revision

Crystal structure of rat prorenin

PDB ID 5mlg

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