5mr9
From Proteopedia
(Difference between revisions)
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<StructureSection load='5mr9' size='340' side='right'caption='[[5mr9]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='5mr9' size='340' side='right'caption='[[5mr9]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5mr9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MR9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr9 OCA], [https://pdbe.org/5mr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mr9 RCSB], [https://www.ebi.ac.uk/pdbsum/5mr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr9 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN] Hirschsprung disease. Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.<ref>PMID:9700200</ref> |
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NRTN_HUMAN NRTN_HUMAN] Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells. |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Aagaard | + | [[Category: Aagaard A]] |
| - | [[Category: Dahl | + | [[Category: Dahl G]] |
| - | [[Category: Oster | + | [[Category: Oster L]] |
| - | [[Category: Roth | + | [[Category: Roth RG]] |
| - | [[Category: Sandmark | + | [[Category: Sandmark J]] |
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Current revision
Ligand-receptor complex.
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Categories: Homo sapiens | Large Structures | Aagaard A | Dahl G | Oster L | Roth RG | Sandmark J
