5mx1

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Current revision (17:52, 8 November 2023) (edit) (undo)
 
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<StructureSection load='5mx1' size='340' side='right'caption='[[5mx1]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
<StructureSection load='5mx1' size='340' side='right'caption='[[5mx1]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5mx1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MX1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MX1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5mx1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MX1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mx1 OCA], [http://pdbe.org/5mx1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mx1 RCSB], [http://www.ebi.ac.uk/pdbsum/5mx1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mx1 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mx1 OCA], [https://pdbe.org/5mx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mx1 RCSB], [https://www.ebi.ac.uk/pdbsum/5mx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mx1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CHAD_HUMAN CHAD_HUMAN]] Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).
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[https://www.uniprot.org/uniprot/CHAD_HUMAN CHAD_HUMAN] Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hohenester, E]]
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[[Category: Hohenester E]]
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[[Category: Paracuellos, P]]
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[[Category: Paracuellos P]]
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[[Category: Cell adhesion]]
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[[Category: Collagen binding]]
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[[Category: Extracellular matrix]]
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[[Category: Leucine-rich repeat]]
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Current revision

Crystal structure of human chondroadherin

PDB ID 5mx1

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