Flurbiprofen
From Proteopedia
(Difference between revisions)
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NSAIDs such as Flurbiprofen work by inhibiting the [[cyclooxygenase]] (COX) enzymes, which convert <scene name='97/973110/Cv/3'>arachidonic acid</scene> to <scene name='42/429113/Cv/4'>prostaglandin H2</scene> (PGH2). PGH2, in turn, is converted by other enzymes to several other [[prostaglandins]] (which are mediators of pain, inflammation, and fever) and to thromboxane A2 (which stimulates platelet aggregation, leading to the formation of blood clots). | NSAIDs such as Flurbiprofen work by inhibiting the [[cyclooxygenase]] (COX) enzymes, which convert <scene name='97/973110/Cv/3'>arachidonic acid</scene> to <scene name='42/429113/Cv/4'>prostaglandin H2</scene> (PGH2). PGH2, in turn, is converted by other enzymes to several other [[prostaglandins]] (which are mediators of pain, inflammation, and fever) and to thromboxane A2 (which stimulates platelet aggregation, leading to the formation of blood clots). | ||
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| + | <scene name='10/1008224/Overall/1'>CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A NON-SELECTIVE INHIBITOR, FLURBIPROFEN</scene> ([[3pgh]]). | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 08:30, 12 November 2023
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