8k39
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of the bacteriophage lambda portal vertex== | |
| - | + | <StructureSection load='8k39' size='340' side='right'caption='[[8k39]], [[Resolution|resolution]] 4.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8k39]] is a 42 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_Lambda Escherichia phage Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K39 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k39 OCA], [https://pdbe.org/8k39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k39 RCSB], [https://www.ebi.ac.uk/pdbsum/8k39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k39 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CAPSD_LAMBD CAPSD_LAMBD] Assembles to form an icosahedral capsid with a T=7 symmetry. The icosahedral capsid is about 60 nm in diameter and composed of 415 major capsid proteins. The assembly is primed by the interaction between capsid assembly protease and portal dodecamer, and major capsid proteins assemble cooperatively to form the procapsid with the help of capsid scaffolding protein. Major capsid protein forms hexons and pentons of the icosahedron. Viral genomic DNA is packaged into the procapsid through the portal vertex (By similarity). The packaging triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. The capsid decoration protein binds the expanded capsid and stabilizes it.[HAMAP-Rule:MF_04133]<ref>PMID:2141087</ref> <ref>PMID:265585</ref> <ref>PMID:8411174</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia phage Lambda]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cheng LP]] | ||
| + | [[Category: Liu HR]] | ||
| + | [[Category: Tan L]] | ||
| + | [[Category: Xiao H]] | ||
Revision as of 07:39, 15 November 2023
Structure of the bacteriophage lambda portal vertex
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