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8wra

From Proteopedia

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m (Protected "8wra" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 8wra is ON HOLD
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==The Crystal Structure of CASP1 from Biortus==
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<StructureSection load='8wra' size='340' side='right'caption='[[8wra]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8wra]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WRA FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wra OCA], [https://pdbe.org/8wra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wra RCSB], [https://www.ebi.ac.uk/pdbsum/8wra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wra ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CASP1_HUMAN CASP1_HUMAN] Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.<ref>PMID:7876192</ref> <ref>PMID:15498465</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Cheng W]]
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[[Category: Guo S]]
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[[Category: Lin D]]
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[[Category: Wang F]]
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[[Category: Yuan Z]]

Revision as of 07:45, 15 November 2023

The Crystal Structure of CASP1 from Biortus

PDB ID 8wra

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OCA

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