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3ldh

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Current revision (09:02, 15 November 2023) (edit) (undo)
 
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<StructureSection load='3ldh' size='340' side='right'caption='[[3ldh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3ldh' size='340' side='right'caption='[[3ldh]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ldh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Squac Squac]. The June 2008 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LDH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ldh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. The June 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Lactate Dehydrogenase'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_6 10.2210/rcsb_pdb/mom_2008_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LDH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ldh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ldh OCA], [https://pdbe.org/3ldh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ldh RCSB], [https://www.ebi.ac.uk/pdbsum/3ldh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ldh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ldh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ldh OCA], [http://pdbe.org/3ldh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ldh RCSB], [http://www.ebi.ac.uk/pdbsum/3ldh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ldh ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LDHA_SQUAC LDHA_SQUAC]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: L-lactate dehydrogenase]]
 
[[Category: Lactate Dehydrogenase]]
[[Category: Lactate Dehydrogenase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Squac]]
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[[Category: Squalus acanthias]]
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[[Category: Adams, M J]]
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[[Category: Adams MJ]]
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[[Category: Buehner, M]]
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[[Category: Buehner M]]
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[[Category: Ford, G C]]
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[[Category: Ford GC]]
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[[Category: Hackert, M L]]
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[[Category: Hackert ML]]
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[[Category: Lentzjunior, P J]]
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[[Category: Lentzjunior PJ]]
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[[Category: Rossmann, M G]]
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[[Category: Rossmann MG]]
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[[Category: Smiley, I E]]
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[[Category: Smiley IE]]
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[[Category: Steindel, S J]]
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[[Category: Steindel SJ]]
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[[Category: White, J L]]
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[[Category: White JL]]
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[[Category: Choh donor]]
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[[Category: Nad acceptor]]
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[[Category: Oxidoreductase]]
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Current revision

A comparison of the structures of apo dogfish m4 lactate dehydrogenase and its ternary complexes

PDB ID 3ldh

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